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HEALTHOCT 01, 2023

Five Medicines You Shouldn't Mix with Coffee

A PIECE BYPRINCE LEONIE
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Discover the unexpected interactions between coffee and five common medications. Learn why your morning brew might affect the efficacy of certain drugs and what symptoms to watch out for. Stay informed and safe with our detailed guide.

Coffee is a daily staple for millions of people worldwide. Its rich aroma and invigorating flavor make it a popular choice for kick-starting the day. However, for those taking certain medications, mixing them with coffee can lead to unwanted, sometimes dangerous, interactions. Here are five medicines you might not know shouldn't be taken with your morning cup of joe:

Antidepressants – Specifically, Monoamine Oxidase Inhibitors (MAOIs)

  • How they work: MAOIs work by increasing the levels of norepinephrine, dopamine, and serotonin in the brain.
  • Why not with coffee: Coffee contains a compound called tyramine. When MAOIs prevent the breakdown of tyramine, its levels can dangerously increase, leading to a hypertensive crisis, which can be life-threatening.
  • Symptoms to watch for: Rapid heartbeat, severe headache, neck stiffness, nausea, and enlarged pupils.
  • Common MAOIs: Phenelzine (Nardil), Tranylcypromine (Parnate).

Thyroid Medications (e.g., Levothyroxine)

  • How they work: They replace or provide more thyroid hormone, which is normally secreted by the thyroid gland.
  • Why not with coffee: Coffee can interfere with the stomach's absorption of thyroid medications. As a result, the medicine might not be as effective if taken with coffee.
  • Recommendation: Wait at least 30 minutes after taking thyroid medication before drinking coffee.

Stimulant Medications (like those for ADHD)

  • How they work: These medicines increase the amount of certain chemicals in the brain to help with concentration.
  • Why not with coffee: Both coffee and stimulant medications increase neurotransmitter activity in the brain. The combination might cause overstimulation, increasing the risk of rapid heartbeat, high blood pressure, and anxiety.
  • Common stimulant medications: Adderall, Concerta, Ritalin.

Iron Supplements

  • How they work: They boost the body's iron levels, often prescribed for anemia.
  • Why not with coffee: The tannins in coffee can bind to the iron, reducing the body's ability to absorb the mineral effectively.
  • Recommendation: Wait at least an hour after taking an iron supplement before consuming coffee.

Bisphosphonates (for osteoporosis)

  • How they work: They inhibit bone resorption, which helps in increasing bone density and strength.
  • Why not with coffee: Just like with iron supplements, the tannins in coffee can interfere with the absorption of bisphosphonates.
  • Common Bisphosphonates: Alendronate (Fosamax), Risedronate (Actonel).

Conclusion

Before starting any medication, it's crucial to consult with a healthcare professional about potential food and drug interactions. If you're a regular coffee drinker, make sure to discuss this habit with your doctor to ensure that you're not unknowingly reducing the effectiveness of your medications or putting yourself at risk for dangerous side effects.

Sources:

  1. Mayo Clinic - MAOIs and diet
  2. Harvard Health - Coffee and Medication Interaction
  3. Journal of Clinical Pharmacy and Therapeutics - Effect of caffeine on circulatory levels of bisphosphonates

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