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HEALTHMAY 18, 2025

Yogurt May Lower Colorectal Cancer Risk

A PIECE BYTHOMPSON ANTHONY
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A large-scale study published in JAMA Network Open finds that consuming yogurt at least twice a week may reduce the risk of developing Bifidobacterium-positive proximal colon cancer by up to 20%. Discover how this common breakfast food could support your long-term colon health.

A powerful case for yogurt in your morning routine

Could a cup of yogurt do more than just improve your digestion? According to a new large-scale study published in JAMA Network Open, the answer appears to be yes. Researchers from the Massachusetts General Brigham and the Harvard T.H. Chan School of Public Health have discovered that a common breakfast food—yogurt—may significantly lower your risk of developing certain types of colorectal cancer.

This finding could offer an accessible, dietary-based prevention strategy for one of the world’s most common and deadly cancers.

📖 Read the study here

🧬 The Study: Yogurt, Gut Bacteria, and Cancer Risk

The researchers analyzed dietary data from over 151,000 participants across two major long-term health studies—the Nurses’ Health Study and the Health Professionals Follow-up Study. Participants completed detailed dietary questionnaires over many years, providing insight into long-term eating habits and health outcomes.

The analysis showed that:

Men who consumed two or more servings of yogurt per week had a 20% lower risk of developing Bifidobacterium-positive proximal colon cancer—a specific and aggressive subtype of colorectal cancer.

This reduction was particularly notable in cancers that occur in the proximal (right) colon, a region more difficult to detect in routine screenings like colonoscopies.

These results are significant because proximal colon cancers are often diagnosed later and have worse prognoses than distal cancers.

🦠 Why Yogurt? The Gut Microbiome Connection

Colorectal cancer doesn’t develop overnight—it’s influenced by a complex web of factors, including inflammation, genetics, and gut health. Yogurt may be beneficial due to its high probiotic content, particularly Bifidobacterium and Lactobacillus, which are known to:

Improve the balance of the gut microbiome

Reduce chronic gut inflammation

Strengthen the intestinal barrier, preventing harmful pathogens or toxins from entering the bloodstream

Modulate immune responses within the colon

The presence of beneficial bacteria may inhibit the growth of pro-inflammatory microbes, which are known to increase the risk of tumor formation.

🥗 How to Add Cancer-Fighting Yogurt to Your Diet

Not all yogurt is created equal. For health-conscious consumers, here are a few tips:

Choose yogurt with live cultures
Look for labels that say “live and active cultures” to ensure you're getting probiotics.

Avoid high-sugar varieties
Flavored yogurts often contain more sugar than a dessert. Opt for plain, unsweetened yogurt and add your own toppings like fresh fruit or honey.

Try Greek or Skyr
These are higher in protein and often contain a denser concentration of probiotics.

Make it a habit
Aim for at least two servings per week, as shown in the study. One serving is typically a 6 oz (170 g) container.

⚠️ Important Caveats

While the research is promising, it doesn’t mean yogurt alone will prevent cancer. The study controlled for multiple lifestyle and dietary variables, and the findings are associative, not causal. However, the evidence supports yogurt as part of a larger pattern of healthy eating that may reduce cancer risk.

More research—including randomized controlled trials—is needed to confirm causality and further explore the microbiome-cancer link.

🔍 Why This Matters

Colorectal cancer is the third most diagnosed cancer worldwide and a leading cause of cancer-related deaths. The good news? Many cases are preventable through dietary changes, physical activity, early screening, and reducing processed meat and alcohol intake.

This study adds to a growing body of literature showing that what we eat directly affects how our genes, immune systems, and microbiomes interact with cancer risk.

🧠 Final Thoughts: A Small Change with Big Impact

Yogurt is more than just a breakfast staple—it’s a microbial powerhouse that could help safeguard your colon. When paired with a diet rich in fiber, fruits, vegetables, and whole grains, it may contribute meaningfully to cancer prevention efforts.

Adding yogurt to your diet is a simple, low-cost habit with potentially high rewards.

📚 Citation:
Zhang X, Cao Y, Wu K, et al. Association of Yogurt Consumption With Risk of Colorectal Cancer Subtypes Defined by Gut Microbial Species. JAMA Netw Open. 2024;7(4):e242532.


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